Phosphate buffers in ophthalmology - Risk of corneal calcification

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چکیده

Phosphate buffers are used in many ophthalmological preparations for adjustment of the pH. The use of eye medication containing a phosphate buffer in patients with pronounced damage to the corneal surface can result in corneal calcification as a result of precipitation of calcium phosphate. On the basis of individual case reports, ophthalmological preparations containing phosphate were subjected to a benefit-risk assessment in Europe in 2011/2012.

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تاریخ انتشار 2013